| Opsoclonus myoclonus. | |
| | |
MedLine Citation:
|
PMID: 22247816 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Opsoclonus myoclonus is a rare autoimmune condition characterized by cerebellar degeneration. It occurs most often as a paraneoplastic syndrome when a cancer remote to the brain induces cerebellar dysfunction that is unrelated to metastases. Half of all cases occur in children with a neuroblastoma. Most adults with opsoclonus myoclonus have neoplastic, infectious, metabolic, or idiopathic etiologies. Signs of cerebellar dysfunction noted at presentation include opsoclonus, myoclonus and ataxia, hence the name "dancing eyes, dancing feet syndrome." Opsoclonus is characterized by rapid, involuntary eye movements that are dysrhythmic and uncoordinated.Neuronal damage is induced by antibodies usually related to the primary pathology. Treatment targets the etiology and also employs steroids, plasmapheresis, immunosuppressive agents, or other anti-inflammatory therapies. Children with opsoclonus myoclonus resulting from a neuroblastoma often retain neurological sequelae. Adult cases of opsoclonus myoclonus with idiopathic or infectious etiologies have a more favorable prognosis than those with neoplastic origins. |
| | |
Authors:
|
Jonathan R Scarff; Bushra Iftikhar; Aniket Tatugade; Jaekyoung Choi; Steven Lippmann |
Related Documents
:
|
21212106 - Delayed experience of volition in gilles de la tourette syndrome. 21486636 - Antibiotic-responsive diarrhea in small animals. 8224566 - Teaching self-feeding skills to patients with rett syndrome. 21710126 - Origin of isolated vertigo in rotational vertebral artery syndrome. 270956 - A biomechanical approach to running injuries. 16272666 - Scurvy in infantile tremor syndrome. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Innovations in clinical neuroscience Volume: 8 ISSN: 2158-8341 ISO Abbreviation: Innov Clin Neurosci Publication Date: 2011 Dec |
Date Detail:
|
Created Date: 2012-01-16 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101549695 Medline TA: Innov Clin Neurosci Country: United States |
Other Details:
|
Languages: eng Pagination: 29-31 Citation Subset: - |
Affiliation:
|
All from University of Louisville School of Medicine, Department of Psychiatry and Behavioral Sciences, Louisville, Kentucky. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Early detection of illicit drug use in teenagers.
Next Document: A Fast Exact k-Nearest Neighbors Algorithm for High Dimensional Search Using k-Means Clustering and ...