Document Detail

Opportunities and risks of using heliox in your clinical practice.
MedLine Citation:
PMID:  16723042     Owner:  NLM     Status:  MEDLINE    
Helium-oxygen mixture (heliox) has been advocated for clinical use since 1934, and there has been a growing array of clinical applications. Until recently, administering heliox has required jury-rigging by modifications and/or extension of available devices not designed for use with heliox. This paper reviews devices required to administer heliox and considers how devices designed to deliver air and/or oxygen have been adapted for use with heliox. Use of devices outside of their design limits adds risk and liability, whereas using Food-and-Drug-Administration cleared devices for heliox administration reduces the risk and liability.
James B Fink
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Respiratory care     Volume:  51     ISSN:  0020-1324     ISO Abbreviation:  Respir Care     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-25     Completed Date:  2006-08-18     Revised Date:  2007-02-13    
Medline Journal Info:
Nlm Unique ID:  7510357     Medline TA:  Respir Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  651-60     Citation Subset:  IM    
Nektar Therapeutics, 2071 Stierlin Court, Mountain View, CA 94043, USA.
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MeSH Terms
Airway Resistance / drug effects
Anoxia / physiopathology
Drug Delivery Systems*
Equipment Design
Helium / administration & dosage*,  therapeutic use
Nebulizers and Vaporizers
Oxygen / administration & dosage*,  therapeutic use
Respiration, Artificial
Tidal Volume / drug effects
Ventilators, Mechanical
Work of Breathing / drug effects
Reg. No./Substance:
58933-55-4/heliox; 7440-59-7/Helium; 7782-44-7/Oxygen
Comment In:
Respir Care. 2006 Nov;51(11):1261-2; author reply 1262-3   [PMID:  17067410 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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