| Opportunistic respiratory pathogens in the oral cavity of the elderly. | |
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MedLine Citation:
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PMID: 20579096 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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The oral cavity of the hospitalized or bedridden elderly is often a reservoir for opportunistic pathogens associated with respiratory diseases. Commensal flora and the host interact in a balanced fashion and oral infections are considered to appear following an imbalance in the oral resident microbiota, leading to the emergence of potentially pathogenic bacteria. The definition of the process involved in colonization by opportunistic respiratory pathogens needs to elucidate the factors responsible for the transition of the microbiota from commensal to pathogenic flora. The regulatory factors influencing the oral ecosystem can be divided into three major categories: the host defense system, commensal bacteria, and external pathogens. In this article, we review the profile of these categories including the intricate cellular interaction between immune factors and commensal bacteria and the disturbance in homeostasis in the oral cavity of hospitalized or bedridden elderly, which facilitates oral colonization by opportunistic respiratory pathogens. |
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Authors:
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Akio Tada; Nobuhiro Hanada |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: FEMS immunology and medical microbiology Volume: 60 ISSN: 1574-695X ISO Abbreviation: FEMS Immunol. Med. Microbiol. Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-11-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9315554 Medline TA: FEMS Immunol Med Microbiol Country: England |
Other Details:
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Languages: eng Pagination: 1-17 Citation Subset: IM |
Copyright Information:
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© 2010 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved. |
Affiliation:
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Department of Oral Health, National Institute of Public Health, Wako, Saitama, Japan. health03jp@ybb.ne.jp |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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