Document Detail

Opportunistic prostate-specific antigen screening in Italy: 6 years of monitoring from the Italian general practice database.
MedLine Citation:
PMID:  20679895     Owner:  NLM     Status:  MEDLINE    
The practice of prostate-specific antigen (PSA) screening has been increasing in Italy despite uncertain scientific evidence and contrary recommendations from most scientific societies. In 2002, a survey of PSA screening diffusion among general practices was performed, looking for screening frequency and age pattern of screened individuals. The objective of this study was to assess whether the features of PSA screening did change after 6 years in the same considered setting. Using the data obtained from 500 Italian general practitioners providing information to the Health Search/CSD Patient database, we selected, for the study purpose 351,091 male individuals. We assumed PSA prescriptions performed during 2005-2008 in individuals without prostate cancer, or benign prostate disease, or urological symptoms history to have a screening purpose. Screening frequency was analyzed in the overall series, by year and by patient's age. Exposure to PSA screening (at least on PSA test in the considered period) of males aged over 50 years raised from 31.4% (confidence interval 95% 31.08-31.70%) during 2002 to 46.4% (confidence interval 95% 46.19-46.68%) during 2008. The highest yearly exposure to PSA screening (55%) and the highest frequency of repeat testing was observed in the 70-79 age range. PSA screening practice has continued to increase in Italy and is often performed in elderly people without any scientific rationale.
Gaetano Giorgio D'Ambrosio; Salvatore Campo; Maurizio Cancian; Serena Pecchioli; Giampiero Mazzaglia
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)     Volume:  19     ISSN:  1473-5709     ISO Abbreviation:  Eur. J. Cancer Prev.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-09-30     Completed Date:  2011-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9300837     Medline TA:  Eur J Cancer Prev     Country:  England    
Other Details:
Languages:  eng     Pagination:  413-6     Citation Subset:  IM    
SIMG Società Italiana di Medicina Generale-Italian College of General Practitioners, Firenze, Italy.
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MeSH Terms
Age Factors
Aged, 80 and over
Databases, Factual
General Practice
Health Care Surveys
Longitudinal Studies
Mass Screening / trends,  utilization*
Middle Aged
Physician's Practice Patterns / statistics & numerical data*,  trends
Prostate-Specific Antigen / blood*
Prostatic Neoplasms / prevention & control*
Reg. No./Substance:
EC Antigen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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