Document Detail

Opisthotonus and other unusual neurological sequelae after outpatient anaesthesia.
MedLine Citation:
PMID:  2386278     Owner:  NLM     Status:  MEDLINE    
Four patients who developed unusual neurological sequelae after outpatient anaesthesia are described. Propofol is strongly implicated as the cause. All four patients were female with no previous history of psychiatric disorder or neurological disease, unpremedicated, and had procedures of duration less than 20 minutes. Hyperreflexia and hypertonicity were present postoperatively and the reactions appeared to be triggered by an external stimulus. Three patients were examined by a neurologist and had a normal electroencephalograph. Two patients were on the same operating list; quality control was carried out on the anaesthetic agents used, and blood samples sent for toxicology showed no abnormalities. Mechanisms underlying these reactions are discussed.
P R Saunders; M N Harris
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Anaesthesia     Volume:  45     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  1990 Jul 
Date Detail:
Created Date:  1990-09-20     Completed Date:  1990-09-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  552-7     Citation Subset:  AIM; IM    
Department of Anaesthetics, St Thomas' Hospital, London.
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MeSH Terms
Ambulatory Surgical Procedures*
Anesthesia, General / adverse effects*
Muscle Hypertonia / chemically induced
Postoperative Complications / etiology*
Propofol / adverse effects*
Reflex, Abnormal / physiology
Spasm / chemically induced*
Reg. No./Substance:
Comment In:
Anaesthesia. 1990 Dec;45(12):1096   [PMID:  2091654 ]
Anaesthesia. 1991 Jun;46(6):508   [PMID:  1904688 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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