Document Detail

Opioid peptides from milk as a possible cause of sudden infant death syndrome.
MedLine Citation:
PMID:  3062337     Owner:  NLM     Status:  MEDLINE    
Milk from breast or baby formula is the exclusive source of nutrition for newborn infants. Short chain opioid peptides such as beta-casomorphins have been isolated from breast milk as well as baby formula. These biologically active peptides are absorbed from the gastrointestinal tract. In infants predisposed to respiratory apnea because of abnormal autonomic nervous system development and respiratory control mechanisms, opioid peptides derived from milk might be one of the etiological factors for sudden infant death syndrome and near miss sudden infant death syndrome.
K Ramabadran; M Bansinath
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical hypotheses     Volume:  27     ISSN:  0306-9877     ISO Abbreviation:  Med. Hypotheses     Publication Date:  1988 Nov 
Date Detail:
Created Date:  1989-02-23     Completed Date:  1989-02-23     Revised Date:  2008-08-15    
Medline Journal Info:
Nlm Unique ID:  7505668     Medline TA:  Med Hypotheses     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  181-7     Citation Subset:  IM    
Department of Anesthesiology, New York University Medical Center, NY 10016.
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MeSH Terms
Apnea / drug therapy
Blood-Brain Barrier
Digestive System / metabolism
Endorphins / metabolism,  pharmacology*,  physiology
Infant, Newborn
Milk / adverse effects*
Milk, Human / analysis
Models, Biological*
Naloxone / therapeutic use
Sudden Infant Death / etiology*
Reg. No./Substance:
0/Endorphins; 465-65-6/Naloxone; 79805-24-6/beta-casomorphins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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