Document Detail

Ophthalmologic follow-up of premature twins and triplets.
MedLine Citation:
PMID:  12841566     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To assess the influence of multiple gestation on the visual apparatus and on the general state of health of premature infants and to investigate the condition of the twin or triplet with the lowest birth weight compared to multiple gestation siblings. METHODS: Seventy-seven premature twins or triplets (8 to 54 months of age) were monitored at the Verona University Ophthalmology Department from November 1995 to November 1999. In another 12 subjects (younger than 8 months), only the neonatal disease records were examined; these subjects were excluded from the ophthalmologic follow-up because they were too young to be tested reliably. The study sample was compared with 120 premature singletons monitored from January 1996 to March 1998. Visual acuity, ocular motility, strabismus, refraction defects, dioptric media, and fundus oculi were assessed. RESULTS: The incidence of retinopathy of prematurity, refraction defects, or strabismus was not significantly different between premature twins or triplets and premature singletons. The twin or triplet with the lowest birth weight was more frequently affected by eye morbidity and the diseases typical of prematurity. This difference, however, was not statistically significant. CONCLUSIONS: Premature infants are at a disadvantage compared to those born at term, irrespective of multiple birth status; multiple gestation adds no risk beyond that due to prematurity.
L Tomazzoli; G Renzi; C Mansoldo
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Publication Detail:
Type:  Comparative Study; Journal Article; Twin Study    
Journal Detail:
Title:  European journal of ophthalmology     Volume:  13     ISSN:  1120-6721     ISO Abbreviation:  Eur J Ophthalmol     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-07-04     Completed Date:  2003-07-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9110772     Medline TA:  Eur J Ophthalmol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  439-44     Citation Subset:  IM    
Institute of Ophthalmology, Borgo Trento Hospital, University of Verona, Verona, Italy.
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MeSH Terms
Birth Weight
Child, Preschool
Diseases in Twins / epidemiology,  etiology*
Eye Diseases / epidemiology,  etiology*
Follow-Up Studies
Gestational Age
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / epidemiology,  etiology*
Italy / epidemiology
Myopia / epidemiology,  etiology
Ocular Motility Disorders / epidemiology,  etiology
Pregnancy, Multiple*
Retinopathy of Prematurity / epidemiology,  etiology
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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