Document Detail


Ophthalmologic and electro-oculographic findings in Gardner's syndrome.
MedLine Citation:
PMID:  3421294     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We examined six patients with Gardner's syndrome, eight first-degree relatives, and 31 age- and sex-matched controls to document the presence, distribution, and morphologic features of congenital hypertrophy of the retinal pigment epithelium. Patients with Gardner's syndrome had multiple, bilateral lesions, with 288 of 346 foci (83%) located posterior to the equator. Linear-shaped congenital hypertrophy of the retinal pigment epithelium, a distinctive finding in these patients, accounted for 44 of 140 large lesions (31%). Despite multifocal fundus involvement, results of electro-oculography were normal in all eyes tested.
Authors:
E A Stein; K D Brady
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  106     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  1988 Sep 
Date Detail:
Created Date:  1988-10-19     Completed Date:  1988-10-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  326-31     Citation Subset:  AIM; IM    
Affiliation:
Department of Ophthalmology, University of Colorado School of Medicine, Denver.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Child
Electrooculography*
Gardner Syndrome / pathology,  physiopathology*
Humans
Hypertrophy
Middle Aged
Pigment Epithelium of Eye / pathology,  physiopathology
Pigmentation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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