Document Detail


Ophthalmic, ultrasonographic findings in primary central nervous system lymphoma with ocular involvement.
MedLine Citation:
PMID:  9143039     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To describe and classify ophthalmic, ultrasonographic findings in patients with primary central nervous system lymphoma with ocular involvement. METHODS: B- and A-scan ultrasonography was performed on the eyes of 13 patients with primary central nervous system lymphoma with ocular involvement. RESULTS: In seven patients, the eyes were the site of initial involvement. In the other six patients, both ocular and central nervous system disease were present at the initial evaluation. All patients had abnormal ultrasonographic findings. The most common were vitreous debris (n = 10), choroidal-scleral thickening (n = 6), and widening of the optic nerve (n = 4). Elevated chorioretinal lesions (n = 3) and retinal detachment (n = 2) were also found. CONCLUSION: Ophthalmic ultrasonography is a useful adjunctive diagnostic technique for characterizing ocular involvement in lymphoma. Ocular lymphoma may present as chorioretinitis, vitreitis and nonspecific uveitis; it produces characteristic, but nonspecific findings on ultrasonography. The diagnosis of ocular involvement is an important factor in determining treatment.
Authors:
R Ursea; M H Heinemann; R H Silverman; L M Deangelis; S W Daly; D J Coleman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Retina (Philadelphia, Pa.)     Volume:  17     ISSN:  0275-004X     ISO Abbreviation:  Retina (Philadelphia, Pa.)     Publication Date:  1997  
Date Detail:
Created Date:  1997-07-17     Completed Date:  1997-07-17     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8309919     Medline TA:  Retina     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  118-23     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Cornell University Medical College, New York, New York 10021, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Anterior Eye Segment / pathology,  ultrasonography
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Biopsy
Brain Neoplasms / pathology,  therapy,  ultrasonography*
Choroid / pathology,  ultrasonography
Eye Neoplasms / pathology,  therapy,  ultrasonography*
Female
Humans
Lymphoma / pathology,  therapy,  ultrasonography*
Male
Middle Aged
Optic Nerve / pathology,  ultrasonography
Retina / pathology,  ultrasonography
Vitrectomy
Vitreous Body / pathology,  ultrasonography
Grant Support
ID/Acronym/Agency:
EY03183/EY/NEI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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