Document Detail

Ophthalmia neonatorum associated with maternal chlamydial infections.
MedLine Citation:
PMID:  878139     Owner:  NLM     Status:  MEDLINE    
An unselected sample of 142 pregnant women had a single cervical culture for C trachomatis at 36 to 40 weeks' gestation. Of these women, 18 (12.7%) had positive cultures, and their infants were followed in postoperative fashion. Of these 18 infants, eight (44%) developed ophthalmia neonatorum. A combination of cultures and conjunctival smears for Giemsa staining and fluorescent-antibody examination for infected cells confirmed the diagnosis in 70% of the infants with conjunctivitis. However, 12 of 18 infants has serum antibodies against genital strain chlamydial antigens at 1 year of age, indicating that a majority of the infants were infected. Four of the infants had superior micropannus at 1 year of age; however, none of the infants had active conjunctivitis nor corneal or conjunctival scars.
J W Chandler; E R Alexander; T A Pheiffer; S P Wang; K K Holmes; M English
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Transactions. Section on Ophthalmology. American Academy of Ophthalmology and Otolaryngology     Volume:  83     ISSN:  0161-6978     ISO Abbreviation:  Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol     Publication Date:    1977 Mar-Apr
Date Detail:
Created Date:  1977-08-25     Completed Date:  1977-08-25     Revised Date:  2008-02-26    
Medline Journal Info:
Nlm Unique ID:  101227536     Medline TA:  Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  302-8     Citation Subset:  IM    
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MeSH Terms
Cervix Uteri / microbiology
Chlamydia Infections*
Chlamydia trachomatis / isolation & purification
Conjunctivitis, Inclusion / diagnosis,  etiology*
Infant, Newborn
Keratitis / etiology
Ophthalmia Neonatorum / etiology
Pregnancy Complications, Infectious*
Tears / immunology
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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