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The Operative Management of Melanoma: Where Does Mohs Surgery Fit In?
MedLine Citation:
PMID:  21585592     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND Melanoma is a life-threatening malignancy. Surgery is the primary management for melanoma, and management guidelines have evolved gradually over a century from radical surgery with lymph node dissection to conservative margin surgery. There are specific rationales and problems with Mohs micrographic (MMS) surgery for managing melanoma. OBJECTIVE To review the literature for the surgical management of melanoma and to understand where MMS fits in this spectrum of management options. CONCLUSIONS MMS should be considered as an option for melanoma surgery, especially when the tumor is found in photodamaged skin. Further randomized prospective clinical trials are needed to select the best therapeutic approach for the treatment of melanoma. Until then, careful margin control is the key for successful tumor removal whether it is standard excision, staged excision, or MMS. The authors have indicated no significant interest with commercial supporters.
Authors:
Kyung Hee Chang; Raymond Dufresne; Antonio Cruz; Gary S Rogers
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-17
Journal Detail:
Title:  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]     Volume:  -     ISSN:  1524-4725     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504371     Medline TA:  Dermatol Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 by the American Society for Dermatologic Surgery, Inc.
Affiliation:
Division of Dermatological Surgery, Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, Rhode Island Division of Dermatologic Surgery, Department of Dermatology, School of Medicine, Tufts University, Boston, Massachusetts.
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