Document Detail

Operation of an air filtration device results in morbidity and mortality in growing chickens (Gallus gallus domesticus).
MedLine Citation:
PMID:  20858358     Owner:  NLM     Status:  MEDLINE    
Environmental conditions may influence experimental outcomes in laboratory animals. In this study, we measured the effects of a vortex air-filtration device (AFD) on growth rate, morbidity, mortality, behavior, and gross pathology in P2a Leghorn chickens (Gallus gallus domesticus) raised from hatchlings to 6 wk of age. Growth rate was reduced in the group exposed to the operating AFD ('AFD on' group) compared with the 2 control groups ('AFD off' and 'Historical' groups). Similarly, 6-wk survival probability and body weight were decreased in the AFD-on group compared with controls. Splenic and cardiac weight indices were lower in the AFD-on and AFD-off groups compared with the Historical group. A progressive increase in the ambient sound level (Historical, 53.5 ± 1.7 dBA; AFD off, 63.6 ± 0.5 dBA; AFD on, 71.8 ± 0.8 dBA) was the only variable found to correlate with the physiologic differences observed across the 3 groups of growing chickens. These findings indicate that experimental outcomes with growing chickens are negatively affected by vortex air-filtration devices.
Todd J Pavek; Helen Valentine; Michele M Bailey
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the American Association for Laboratory Animal Science : JAALAS     Volume:  49     ISSN:  1559-6109     ISO Abbreviation:  J. Am. Assoc. Lab. Anim. Sci.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-22     Completed Date:  2011-06-08     Revised Date:  2011-07-25    
Medline Journal Info:
Nlm Unique ID:  101269489     Medline TA:  J Am Assoc Lab Anim Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  578-82     Citation Subset:  IM    
Center for Animal Resources and Education, Cornell University, Ithaca, New York, USA.
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MeSH Terms
Behavior, Animal
Body Weight
Chickens / growth & development,  physiology*
Heart / growth & development
Housing, Animal*
Noise / adverse effects*
Spleen / growth & development

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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