Document Detail


Open vessel mode microwave-assisted synthesis of 2-oxazolines from carboxylic acids.
MedLine Citation:
PMID:  21533007     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Microwave-assisted synthesis of 2-oxazolines from carboxylic acids using the open vessel technique is described. This efficient method involves direct condensation of carboxylic acids with excess 2-amino-2-methyl-1-propanol at 170 °C to give the corresponding 2-oxazolines in moderate to excellent yields.
Authors:
Rishi Sharma; Subramanian K Vadivel; Richard I Duclos; Alexandros Makriyannis
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Tetrahedron letters     Volume:  50     ISSN:  0040-4039     ISO Abbreviation:  -     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2011-5-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984819R     Medline TA:  Tetrahedron Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  5780-5782     Citation Subset:  -    
Affiliation:
Center for Drug Discovery, Northeastern University, 360 Huntington Avenue, 116 Mugar Life Sciences Building, Boston, MA, 02115, USA.
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
R03 DA024842-01//NIDA NIH HHS; R03 DA024842-02//NIDA NIH HHS

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