Document Detail


The Open-Artery Hypothesis: An Overview.
MedLine Citation:
PMID:  10639257     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The open artery hypothesis postulates salutary effects distinct from myocardial salvage referable to infarct related arterial patency. Short and long term clinical trials, as well as studies in animal models have suggested clinical benefit in patients with sustained infarct related arterial patency. Mechanisms of benefit are not entirely clear, but probably relate to mitigation of post infarction left ventricular remodeling and improvement in several electrophysiologic parameters. The effect of infarct related arterial patency on post infarction prognosis, presumed mechanisms of benefit and noninvasive assessment of arterial patency are summarized in this review.
Authors:
Kimmelstiel; Salem
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Journal of thrombosis and thrombolysis     Volume:  4     ISSN:  1573-742X     ISO Abbreviation:  J. Thromb. Thrombolysis     Publication Date:  1997  
Date Detail:
Created Date:  2000-01-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9502018     Medline TA:  J Thromb Thrombolysis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  227-237     Citation Subset:  -    
Affiliation:
Tufts University School of Medicine; Adult Cardiac Catheterization, Laboratory and Ambulatory Cardiology, New England Medical Center Boston, Massachusetts, USA.
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