| Opalina ranarum: inhibitory effect of 13-cis-retinoic acid or retinyl palmitate on the induction of cyst formation. | |
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MedLine Citation:
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PMID: 6413239 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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20-Methylcholanthrene induced the encystment of Opalina ranarum when injected into its host, Rana ridibunda. Also, urine of frogs injected with this hydrocarbon induced encystment of the parasites. It is speculated that methylcholanthrene or its metabolites reach the parasites in the recta of the frogs and stimulate the parasites to encyst. Injections of frogs with methylcholanthrene and 13-cis-retinoic acid failed to induce cyst formation in the opalinids. Moreover, encystment of the parasite was lessened when the host was injected with methylcholanthrene and retinyl palmitate. Urine of frogs injected with methylcholanthrene and 13-cis-retinoic acid failed to induce cyst formation in the parasites. Moreover, urine of frogs injected with this hydrocarbon and retinyl palmitate lessened the induction of cyst formation in the parasites in vitro. It is suggested that 13-cis-retinoic acid as well as retinyl palmitate inhibits methylcholanthrene-induced cyst formation of the opalinids. |
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Authors:
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I A Sadek |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Experimental parasitology Volume: 56 ISSN: 0014-4894 ISO Abbreviation: Exp. Parasitol. Publication Date: 1983 Oct |
Date Detail:
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Created Date: 1983-11-23 Completed Date: 1983-11-23 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370713 Medline TA: Exp Parasitol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 241-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Ciliophora / drug effects*, physiology Female Isotretinoin Male Methylcholanthrene / pharmacology Ranidae Tretinoin / pharmacology* Urine Vitamin A / analogs & derivatives*, pharmacology |
| Chemical | |
Reg. No./Substance:
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11103-57-4/Vitamin A; 302-79-4/Tretinoin; 4759-48-2/Isotretinoin; 56-49-5/Methylcholanthrene; 79-81-2/retinol palmitate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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