Document Detail

Oocyte donation: comparison between recipients from different age groups.
MedLine Citation:
PMID:  8150907     Owner:  NLM     Status:  MEDLINE    
Oocyte donation was carried out in 87 patients in 141 replacement cycles. These patients received oocytes from 108 women undergoing assisted reproductive technology procedures at our centre. Standardized hormonal replacement therapy and in-vitro fertilization procedures were performed. We divided recipients into four groups according to their age (group A, 21-35 years; B, 36-40 years; C, 41-49 years; and D, 50-61 years). Oocytes donors were 21-35 years old, and equally spread across these different age groups. There were significant differences in the pregnancy and implantation rates according to the age of the recipients; which were 45% and 23% respectively in women 21-35 years old (group A) versus 23% and 10% in women 41-49 years old (group C). A comparison of data between oocyte donors and young recipients, with similar results in donors and young recipients, with pregnancy rates of 45% and 42% and implantation rates of 23% and 19.5% respectively. Statistically significant differences were found between donors and the older recipients, pregnancy rates being 43% versus 23%, and implantation rates 18% versus 10%. These data seem to demonstrate a lesser likelihood of pregnancy and implantation in older recipients because of increasing uterine age.
C Flamigni; A Borini; F Violini; L Bianchi; L Serrao
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  8     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1993 Dec 
Date Detail:
Created Date:  1994-05-12     Completed Date:  1994-05-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  2088-92     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, University of Bologna, Italy.
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MeSH Terms
Aging / physiology*
Endometrium / physiology*
Middle Aged
Oocytes / physiology*
Tissue Donors*

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