Document Detail


Ontogeny, growth and development of the small intestine: Understanding pediatric gastroenterology.
MedLine Citation:
PMID:  20143457     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Throughout our lifetime, the intestine changes. Some alterations in its form and function may be genetically determined, and some are the result of adaptation to diet, temperature, or stress. The critical period programming of the intestine can be modified, such as from subtle differences in the types and ratios of n3:m6 fatty acids in the diet of the pregnant mother, or in the diet of the weanlings. This early forced adaptation may persist in later life, such as the unwanted increased intestinal absorption of sugars, fatty acids and cholesterol. Thus, the ontogeny, early growth and development of the intestine is important for the adult gastroenterologist to appreciate, because of the potential for these early life events to affect the responsiveness of the intestine to physiological or pathological challenges in later life.
Authors:
Laurie A Drozdowski; Tom Clandinin; Alan B R Thomson
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Publication Detail:
Type:  Editorial; Review    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  16     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-09     Completed Date:  2010-05-04     Revised Date:  2010-09-27    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  787-99     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological
Adult
Animals
Biological Transport
Cell Differentiation
Cell Proliferation
Child
Dietary Carbohydrates / metabolism
Dietary Fats / metabolism
Dietary Proteins / metabolism
Female
Humans
Infant, Newborn
Intestinal Absorption*
Intestinal Mucosa / embryology,  growth & development*,  metabolism
Intestine, Small / embryology,  growth & development*,  metabolism
Milk Proteins / metabolism
Nutritional Status
Pregnancy
Chemical
Reg. No./Substance:
0/Dietary Carbohydrates; 0/Dietary Fats; 0/Dietary Proteins; 0/Milk Proteins
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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