Document Detail


Ontogeny of behavioral sensitivity to glycine in the chick embryo.
MedLine Citation:
PMID:  7409326     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Strychnine (STR), glycine (GLY), and gamma-aminobutyric acid (GABA) were injected intravenously into 6- and 7-day chick embryos and subsequent effects upon spontaneous motility were observed. In 7-day embryos STR alone increased motility and when injected simultaneously with GLY antagonized the GLY-induced motility decrements; STR did not antagonize GABA-induced motility decrements. In 6-day embryos STR injected alone had no effect on motility, but did antagonize motility decrements induced by the simultaneous injection of GLY; again STR did not antagonize GABA-induced motility decrements.
Authors:
J Reitzel; R W Oppenheim
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Developmental psychobiology     Volume:  13     ISSN:  0012-1630     ISO Abbreviation:  Dev Psychobiol     Publication Date:  1980 Sep 
Date Detail:
Created Date:  1980-11-25     Completed Date:  1980-11-25     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0164074     Medline TA:  Dev Psychobiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  455-61     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Animals
Behavior, Animal / drug effects*
Chick Embryo
Glycine / pharmacology*
Motor Activity / drug effects
Strychnine / pharmacology
gamma-Aminobutyric Acid / pharmacology
Grant Support
ID/Acronym/Agency:
16598//PHS HHS
Chemical
Reg. No./Substance:
56-12-2/gamma-Aminobutyric Acid; 56-40-6/Glycine; 57-24-9/Strychnine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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