Document Detail

Ontogenetic and phylogenetic evaluation of the presence of fibrin-type fibrinoid in the villous haemochorial placenta.
MedLine Citation:
PMID:  9290158     Owner:  NLM     Status:  MEDLINE    
The hypothesis that fibrin type fibrinoid deposition on villi is unique to the term human placenta was tested. Bright-field microscopy was used to examine sections of first and second trimester human placental villi and tissues from three animal species that have villous haemochorial placentae similar to the human: the armadillo, the baboon and the rhesus. Sections stained with haematoxylin and eosin showed fibrin type fibrinoid deposits were hypocellular, eosinophilic masses attached to the surface of villi examined from both the human and the animal species. The deposits were located at discontinuities in the syncytiotrophoblast layer, and the fibrinoid provided a matrix for trophoblast re-epithelization of the villous surface. It is concluded that fibrin-type fibrinoid is not unique to the term human placenta. The presence of the syncytiotrophoblast discontinuities associated with the fibrinoid deposition must be considered in models of maternal-fetal exchange in the villous haemochorial placenta.
D M Nelson; P E Swanson; B B Davison; G B Baskin; A C Enders
Related Documents :
9085198 - Endothelins-1, 2 and 3 are released in vitro from the human bilaterally perfused placenta.
24041008 - Maternal influenza-like illness, medication use during pregnancy and risk of congenital...
3318828 - The corticotropin releasing hormone gene is expressed in human placenta.
12852418 - The human first trimester gestational sac limits rather than facilitates oxygen transfe...
10776008 - Effects of low-dose aspirin on uterine and fetal blood flow during pregnancy: results o...
24374988 - Severe bioprosthetic mitral valve stenosis in pregnancy.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Placenta     Volume:  18     ISSN:  0143-4004     ISO Abbreviation:  Placenta     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1997-10-15     Completed Date:  1997-10-15     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8006349     Medline TA:  Placenta     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  605-8     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Washington University School of Medicine, St Louis, Missouri, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Chorionic Villi / chemistry*
Coloring Agents
Eosine Yellowish-(YS)
Fibrin / analysis*
Immunoenzyme Techniques
Macaca mulatta
Grant Support
Reg. No./Substance:
0/Coloring Agents; 17372-87-1/Eosine Yellowish-(YS); 517-28-2/Hematoxylin; 9001-31-4/Fibrin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Hypoxia downregulates continuous and interleukin-1-induced expression of human chorionic gonadotropi...
Next Document:  Renal accumulation and distribution of hyaluronan after ureteral obstruction.