Document Detail

Ontogenesis of corticotropes and lactotropes in situ in the pituitary gland of the hamster. An immunohistochemical study.
MedLine Citation:
PMID:  3019551     Owner:  NLM     Status:  MEDLINE    
The development of corticotropes and lactotropes was investigated in the golden Syrian hamster using an anti-porcine ACTH antiserum and a homologous anti-hamster PRL antiserum. Oval corticotropes were first visible in the ventral region of the pars distalis at 13 days of gestation. By the end of gestation, corticotropes were found throughout the pars distalis and in the pars intermedia. Corticotropes in the pars distalis of postnatal hamsters were either round or irregularly-shaped, often appearing in clusters. Throughout development, corticotropes often appeared to be surrounding other cells. Scarce, very small lactotropes were first observed in the pars distalis of hamsters on the first postnatal day. The number of these cells, which were either round or polyhedral, increased dramatically between 4 and 20 days of postnatal life. These observations indicate that the sequence of appearance of corticotropes and lactotropes in the hamster is similar to that in other species and that lactotropes are confined to the pars distalis of postnatal hamsters.
G T Campbell; J Wagoner; K T Borer; R P Kelch; K Corley
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Cell and tissue research     Volume:  245     ISSN:  0302-766X     ISO Abbreviation:  Cell Tissue Res.     Publication Date:  1986  
Date Detail:
Created Date:  1986-11-20     Completed Date:  1986-11-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0417625     Medline TA:  Cell Tissue Res     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  673-9     Citation Subset:  IM    
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MeSH Terms
Adrenocorticotropic Hormone / analysis*
Immune Sera
Immunoenzyme Techniques
Pituitary Gland / cytology,  embryology*
Prolactin / analysis*
Grant Support
Reg. No./Substance:
0/Immune Sera; 9002-60-2/Adrenocorticotropic Hormone; 9002-62-4/Prolactin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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