Document Detail

Onset and duration periods of articaine and lidocaine on maxillary infiltration.
MedLine Citation:
PMID:  15887505     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: The aim of this study was to compare the onset and duration of pulpal anesthesia by maxillary infiltration using 2% lidocaine with 1:100,000 epinephrine, 4% articaine with 1:200,000 epinephrine, and 4% articaine with 1:100,000 epinephrine. METHOD AND MATERIALS: Twenty healthy patients randomly received 1.8 mL of one of the three local anesthetics during operative dentistry procedures of low complexity on three maxillary posterior teeth. Onset and duration were determined using an electric pulp tester. RESULTS: The mean values for pulpal onset were 2.8, 1.6, and 1.4 minutes and for pulpal duration were 39.2, 56.7, and 66.3 minutes, respectively, for 2% lidocaine with 1:100,000 epinephrine, 4% articaine with 1:200,000 epinephrine, and 4% articaine with 1:100,000 epinephrine. Statistical analysis by the Kruskal-Wallis nonparametric test showed significant differences with better results (shorter onset and longer duration periods) for both articaine solutions compared with the lidocaine solution. Although 4% articaine with 1:100,000 epinephrine clinically presented the shortest onset and the longest duration periods, there was no statistically significant difference between the articaine solutions. CONCLUSION: Both articaine solutions produced shorter onset and longer duration of pulpal anesthesia by maxillary infiltration than the lidocaine solution did. Statistical analysis did not confirm better clinical results of 4% articaine with 1:100,000 epinephrine than with 4% articaine with 1:200,000 epinephrine.
Carina Gisele Costa; Isabel Peixoto Tortamano; Rodney Garcia Rocha; Carlos Eduardo Francischone; Nicolau Tortamano
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Quintessence international (Berlin, Germany : 1985)     Volume:  36     ISSN:  0033-6572     ISO Abbreviation:  Quintessence Int     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-05-12     Completed Date:  2005-07-19     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0342677     Medline TA:  Quintessence Int     Country:  England    
Other Details:
Languages:  eng     Pagination:  197-201     Citation Subset:  D    
Department of Integrated Clinic and Prosthodontics, Faculty of Dentistry, Uningá University, Maringá, Paraná, Brazil.
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MeSH Terms
Anesthesia, Dental / methods*
Anesthesia, Local / methods*
Anesthetics, Local / administration & dosage*
Carticaine / administration & dosage*
Dental Pulp Test
Lidocaine / administration & dosage*
Statistics, Nonparametric
Reg. No./Substance:
0/Anesthetics, Local; 137-58-6/Lidocaine; 23964-58-1/Carticaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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