Document Detail

Onion and garlic intake and the odds of benign prostatic hyperplasia.
MedLine Citation:
PMID:  17991535     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To analyze the relationship between onion and garlic intake and benign prostatic hyperplasia (BPH), using data from a multicenter case-control study conducted in Italy. METHODS: A multicenter case-control study of 1369 patients with BPH and 1451 controls, admitted to the same hospitals for a wide spectrum of acute, non-neoplastic conditions, was conducted in Italy between 1991 and 2002. Information was collected by trained interviewers using a validated and reproducible food frequency questionnaire. Multivariate odds ratios (ORs) and 95% confidence intervals (CIs) were obtained after allowance for recognized confounding factors and energy intake. RESULTS: Compared with nonusers, the multivariate ORs for the highest category of onion and garlic intake were 0.41 (95% CI 0.24 to 0.72) and 0.72 (95% CI 0.57 to 0.91), respectively. The combined OR for frequent users versus nonusers of both onion and garlic was 0.65 (95% CI 0.49 to 0.86). The inverse relationships were consistent across age strata. CONCLUSIONS: This uniquely large data set from European populations showed an inverse association between allium vegetable consumption and BPH.
Carlotta Galeone; Claudio Pelucchi; Renato Talamini; Eva Negri; Luigino Dal Maso; Maurizio Montella; Valerio Ramazzotti; Silvia Franceschi; Carlo La Vecchia
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Urology     Volume:  70     ISSN:  1527-9995     ISO Abbreviation:  Urology     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-11-09     Completed Date:  2007-12-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0366151     Medline TA:  Urology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  672-6     Citation Subset:  IM    
Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
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MeSH Terms
Case-Control Studies
Middle Aged
Odds Ratio
Prostatic Hyperplasia / epidemiology,  prevention & control*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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