Document Detail

Ongoing pregnancy after ICSI of frozen-thawed PESA-retrieved spermatozoa and IVF in a controlled natural cycle.
MedLine Citation:
PMID:  15949225     Owner:  NLM     Status:  MEDLINE    
The recovery of a mature oocyte from a natural cycle followed by IVF (nIVF) is an attractive alternative to conventional IVF, involving ovarian stimulation, in the treatment of female infertility. Similarly, surgical recovery of spermatozoa from the epididymis by percutaneous sperm aspiration (PESA) has simplified the treatment of men with obstructive azoospermia. A couple sought treatment for diminished ovarian reserve and male factor infertility using IVF. A mature oocyte was retrieved and was inseminated by intracytoplasmic sperm injection (ICSI), following recovery of spermatozoa by PESA. A good quality embryo was transferred. A viable pregnancy was confirmed by ultrasound scan. A healthy baby boy was delivered naturally at 37 weeks gestation. This study reports the first ongoing clinical pregnancy and subsequent birth resulting from ICSI of spermatozoa retrieved by PESA into an oocyte recovered during a natural cycle. The use of a combination of less invasive assisted reproductive techniques (PESA and nIVF) can overcome barriers to fertility.
Isaac Jacques Kadoch; Simon J Phillips; Robert Hemmings; Louise Lapensée; Bernard Couturier; François Bissonnette
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  10     ISSN:  1472-6483     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-06-13     Completed Date:  2005-08-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  England    
Other Details:
Languages:  eng     Pagination:  650-2     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Université de Montréal and Saint Luc Hospital (CHUM), 1058 rue Saint-Denis, Montréal, Québec, Canada H2X 3J4.
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MeSH Terms
Embryo Transfer
Fertilization in Vitro*
Ovulation Induction / methods
Pregnancy Outcome
Semen Preservation*
Sperm Injections, Intracytoplasmic
Tissue and Organ Harvesting / methods*

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