Document Detail

Results of heparin-bonded ePTFE-covered stents for chronic occlusive superficial femoral artery disease.
MedLine Citation:
PMID:  22342154     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to assess the 1-year patency rates of heparin-bonded covered stents in the treatment of chronic occlusive disease of the superficial femoral artery (SFA).
METHODS: All patients treated with a heparin-bonded endograft between April 2009 and October 2010 for chronic occlusive disease of the SFA were prospectively gathered in a database and retrospectively analyzed. Primary, primary-assisted, and secondary patency rates, assessed by ultrasound scanning, were analyzed at 1-year, as were the complication rates and mortality.
RESULTS: A total of 56 limbs were treated with a heparin-bonded covered stent in 53 patients for chronic ischemia Rutherford category 3 (n = 36), 4 (n = 5), 5 (n = 11), and 6 (n = 1). Lesions were classified as TransAtlantic Inter-Society Consensus (TASC)-2-B (n = 9), C (n = 14), and D (n = 33), and the mean treated lesion length was 18.5 ± 7.7 cm. Postoperative complications occurred in 7.5%, including hematoma (n = 1), edema (n = 1), pneumonia (n = 1), and urinary retention (n = 1), and the 30-day mortality rate was 0%. The mean follow-up was 413 ± 208 days. At 1 year, the primary patency was 76%, the primary-assisted patency 82%, and the secondary patency 89%. The limb salvage rate was 100%.
CONCLUSIONS: Heparin-bonded covered stents seem to provide a valid alternative to surgical treatment of long occlusive lesions in the SFA. Randomized trials and long-term data are required before considering the technique as a new standard of care.
Mare M A Lensvelt; Wilbert M Fritschy; Jacques A van Oostayen; Suzanne Holewijn; Clark J Zeebregts; Michel M P J Reijnen
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Publication Detail:
Type:  Journal Article     Date:  2012-02-17
Journal Detail:
Title:  Journal of vascular surgery     Volume:  56     ISSN:  1097-6809     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-07-03     Completed Date:  2012-09-20     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  118-25     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.
Department of Surgery, Rijnstate Hospital, Arnhem, The Netherlands.
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MeSH Terms
Ankle Brachial Index
Arterial Occlusive Diseases / surgery*,  ultrasonography
Chronic Disease
Coated Materials, Biocompatible*
Femoral Artery / pathology*,  surgery*,  ultrasonography
Peripheral Vascular Diseases / surgery*,  ultrasonography
Postoperative Complications
Prospective Studies
Treatment Outcome
Vascular Patency
Reg. No./Substance:
0/Coated Materials, Biocompatible; 9002-84-0/Polytetrafluoroethylene; 9005-49-6/Heparin

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