Document Detail

One-year prognosis of primary ventricular fibrillation complicating acute myocardial infarction. The GISSI (Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto miocardico) investigators.
MedLine Citation:
PMID:  2565684     Owner:  NLM     Status:  MEDLINE    
The 1-year prognosis of 293 patients discharged alive from the hospital after acute myocardial infarction (AMI), who experienced primary ventricular fibrillation (VF) in the acute phase, was compared with that of a reference group of 6,337 patients identified from the same population included in the Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto miocardico (GISSI) trial. There was no difference in the 6- and 12-month mortality between the patients with primary VF and the reference group (3.7 vs 2.7% and 4.1 vs 4.2%, respectively). Survival of the 2 groups was also similar when patients were stratified according to infarct site (anterior and posterior), and whether or not they received treatment with streptokinase during AMI. Thus, long-term mortality of patients discharged alive after AMI complicated by primary VF is low and is not influenced by previous fibrinolytic therapy or by infarct site. The excess mortality of patients with primary VF is confined to the hospital phase, after which survivors represent a low-risk subgroup.
A Volpi; A Cavalli; M G Franzosi; A Maggioni; F Mauri; E Santoro; G Tognoni
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  63     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1989 May 
Date Detail:
Created Date:  1989-06-07     Completed Date:  1989-06-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1174-8     Citation Subset:  AIM; IM    
Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto miocardico (GISSI) Coordinating Center, Milan, Italy.
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MeSH Terms
Adrenergic beta-Antagonists / administration & dosage
Anti-Arrhythmia Agents / administration & dosage
Follow-Up Studies
Myocardial Infarction / complications*,  drug therapy,  mortality
Streptokinase / therapeutic use
Ventricular Fibrillation / etiology*,  mortality
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Anti-Arrhythmia Agents; EC 3.4.-/Streptokinase

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