| One-year outcomes of patients with the zotarolimus-eluting coronary stent: RESOLUTE International Registry. | |
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MedLine Citation:
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PMID: 22334317 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Aims: To provide clinical outcome data from everyday practice for the new generation Resolute zotarolimus-eluting stent (R-ZES). Methods and results: Patients were eligible if placement of ≥1 R-ZES was intended. There were no restrictions on clinical indication, number of treated vessels, and lesion characteristics. The primary endpoint was the adjudicated cumulative 1-year incidence of cardiac death and target vessel myocardial infarction. Twenty-five per cent of the patients were randomly selected for monitoring. We recruited 2,349 patients with 3,147 lesions (1.6±1.0 stents per patient); 46.0% of patients had acute coronary syndrome, 30.5% were diabetic, and ≥1 complex criterion for stent placement was present in 67.5% of patients. One-year follow-up was complete in 97.9% of patients. The 1-year incidence of the primary endpoint was 4.3% (95% CI: 3.5% to 5.2%) and for ARC definite and probable stent thrombosis, 0.9% (0.5% to 1.3%). Clinically driven target lesion revascularisation and target lesion failure were 3.4% (2.7% to 4.3%) and 7.0% (6.0% to 8.2%), respectively. These findings were consistent across all lesion and patient subsets analysed. There were no significant differences in outcomes between monitored and unmonitored patients. Conclusions: In everyday practice, the R-ZES performed similarly well as in the RESOLUTE All Comers randomised trial. |
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Authors:
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Franz-Josef Neumann; Petr Widimsky; Jorge A Belardi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology Volume: 7 ISSN: 1969-6213 ISO Abbreviation: EuroIntervention Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-02-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101251040 Medline TA: EuroIntervention Country: France |
Other Details:
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Languages: eng Pagination: 1181-8 Citation Subset: IM |
Affiliation:
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Heart Center Bad Krozingen, Bad Krozingen, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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