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One-year outcome from an all-comers population of patients with ST-segment elevation myocardial infarction treated with biolimus-eluting stent with biodegradable polymer.
MedLine Citation:
PMID:  25115927     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Objectives: To evaluate the performance of biolimus-eluting stent (BES) in patients with ST- elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI) in a real world clinical scenario. Background: Randomized studies suggest that the BES with biodegradable polymer is more effective and safe than early generation coronary stents in patients with STEMI. Methods: We included all consecutive STEMI patients undergoing PCI in this prospective, multicenter registry. The primary endpoint of the study was the rate of major adverse cardiac events (MACE), a composite of cardiac death, recurrent myocardial infarction (MI) and ischemia-driven target vessel revascularization at 1-year follow-up. Results: Between June and December 2012 we enrolled 311 STEMI patients. The primary endpoint occurred in 3.2% (95% confidence interval [CI]: 1.6-5.8) of patients: cardiac death, re-infarction and ischemia-driven TVR occurred in 2.3%, 1.3% and 0.6% of patients, respectively. One-year MACE-free survival was 96,8±1.0%. Conclusions: In a real-world cohort of STEMI patients undergoing PCI, the use of BES is associated with good one-year clinical outcome. These results confirm and expand previous findings showing the efficacy and safety of BES in the setting of randomized trials. © 2014 Wiley Periodicals, Inc.
Authors:
Fabrizio Tomai; Leonardo De Luca; Luca Altamura; Francesco Versaci; Mauro Pennacchi; Igino Proietti; Anna S Ghini; Pierfrancesco Corvo; Giovanni De Persio; Alessandro Petrolini; Antonella Tommasino; Gennaro Sardella
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-8-12
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  -     ISSN:  1522-726X     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-8-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Wiley Periodicals, Inc., a Wiley company.
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