Document Detail


One-month-old infant with multiple ulcers of stomach, small bowel, large bowel, and protein-losing enteropathy: case report.
MedLine Citation:
PMID:  11200486     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Multiple inflammatory ulcers of the gastrointestinal tract are rare in young infants. Most cases are caused by infectious organisms, vasculitis, or an autoimmune process. We report a 1-month-old infant who was healthy until he presented with an inflammatory mesenteric cyst, and multiple ulcers of the stomach, duodenum, jejunum, ileum, and colon. Histologically, the ulcerations were sharply demarcated, full thickness, and filled with macrophages. He had a low serum albumin and IgG due to protein-losing enteropathy. He was treated with supportive care and immunomodulating drugs. The gastrointestinal inflammation resolved by 3 and 1/2 years of age. The medications were withdrawn at 5 and 1/2 years of age he had no relapse of clinical symptoms. He continues to have asymptomatic mild hypoalbuminemia and low serum IgG. We could not find a report of a similar clinical presentation and outcome.
Authors:
T C Stephen; R W Bendon
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society     Volume:  4     ISSN:  1093-5266     ISO Abbreviation:  Pediatr. Dev. Pathol.     Publication Date:    2001 Jan-Feb
Date Detail:
Created Date:  2001-01-26     Completed Date:  2001-03-08     Revised Date:  2006-05-08    
Medline Journal Info:
Nlm Unique ID:  9809673     Medline TA:  Pediatr Dev Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  100-3     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University of Louisville, KY 40202, USA.
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MeSH Terms
Descriptor/Qualifier:
Albumins / analysis
Drug Therapy, Combination
Humans
Immunoglobulin G / blood
Infant
Intestinal Diseases / blood,  etiology,  pathology*,  therapy
Intestine, Large / pathology*
Intestine, Small / pathology*
Male
Protein-Losing Enteropathies / blood,  complications,  pathology*,  therapy
Stomach Ulcer / blood,  etiology,  pathology*,  therapy
Ulcer / blood,  etiology,  pathology*,  therapy
Chemical
Reg. No./Substance:
0/Albumins; 0/Immunoglobulin G

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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