Document Detail


One-legged endurance training: leg blood flow and oxygen extraction during cycling exercise.
MedLine Citation:
PMID:  22059600     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Aim:  As a consequence of enhanced local vascular conductance, perfusion of muscles increases with exercise intensity to suffice the oxygen demand. However, when maximal oxygen uptake (VO(2) max) and cardiac output are approached, the increase in conductance is blunted. Endurance training increases muscle metabolic capacity, but to what extend that affects regulation of muscle vascular conductance during exercise is unknown. Methods:  Seven weeks of one-legged endurance training was carried out by twelve subjects. Pulmonary VO(2) during cycling and one-legged cycling was tested before and after training while VO(2) of the trained leg (TL) and control leg (CL) during cycling was determined after training. Results: VO(2) max for cycling was unaffected by training although one-legged VO(2) max became 6.7 (2.3)% (mean±SE) larger with TL than with CL. Also TL citrate synthase activity was higher (30 (12)%; P<0.05). With the two legs working at precisely the same power during cycling at high intensity (n=8), leg oxygen uptake was 21 (8)% larger for TL than for CL (P<0.05) with oxygen extraction being 3.5 (1.1)% higher (P<0.05) and leg blood flow tended to be higher by 16.0 (7.0)% (P<0.06). Conclusion:  That enhanced VO(2) max for the trained leg had no implication for cycling VO(2) max supports that there is a central limitation to VO(2) max during whole-body exercise. However, the metabolic balance between the legs was changed during high intensity exercise since oxygen delivery and oxygen extraction were higher in the trained leg, suggesting that endurance training ameliorates blunting of leg blood flow and oxygen uptake during whole-body exercise.
Authors:
B Rud; O Foss; P Krustrup; N H Secher; J Hallén
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-7
Journal Detail:
Title:  Acta physiologica (Oxford, England)     Volume:  -     ISSN:  1748-1716     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101262545     Medline TA:  Acta Physiol (Oxf)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Scandinavian Physiological Society.
Affiliation:
Norwegian School of Sport Sciences, Oslo, Norway Sport and Health Sciences, College of Life and Environmental Sciences, University of Exeter, United Kingdom Department of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark Copenhagen Muscle Research Centre, Department of Anaesthesia, Rigshospitalet, Denmark.
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