Document Detail

One-knot microvascular anastomosis. An experimental study in rats.
MedLine Citation:
PMID:  3553457     Owner:  NLM     Status:  MEDLINE    
Experimental microvascular anastomosis using a glutide copolymer (lactide:glycolide, 80:20) as an external splint was undertaken in 33 rats between the carotid artery and the jugular vein. Both vessels were dissected free over a 1-cm length and cut at the cranial end of the dissected part. The carotid artery was then introduced into a glutide pipe-splint. The arterial wall was turned 180 degrees over the edge of the splint. This reflected artery wall and the glutide were covered by the freed-up jugular vein. One stitch was made around the vein, the artery, and the glutide in a manner similar to binding steel wire over a barrel. Thus, the "one-knot anastomosis" was completed. The patency rate at the anastomosed site was 100%, confirmed by angiography in 30 rats and by direct surgery in three. The time required to produce the anastomosis was between 5 and 7 minutes. Light microscopic observation showed that there was no obstruction by thrombus formation at 1 and 5 weeks after the anastomotic surgery. This technique may be clinically applicable for extracranial-intracranial bypass surgery, reconstruction of venous sinuses, and other vascular procedures.
H Iwasa; F Sato; H Shimabukuro; N Yamada; Y Ikada; S H Hyon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  66     ISSN:  0022-3085     ISO Abbreviation:  J. Neurosurg.     Publication Date:  1987 May 
Date Detail:
Created Date:  1987-06-05     Completed Date:  1987-06-05     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  764-7     Citation Subset:  AIM; IM    
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MeSH Terms
Arteriovenous Shunt, Surgical / instrumentation,  methods*
Blood Vessel Prosthesis
Carotid Arteries / surgery
Jugular Veins / surgery
Microsurgery / instrumentation,  methods*
Polyglactin 910 / therapeutic use
Rats, Inbred Strains
Suture Techniques* / instrumentation
Vascular Surgical Procedures / instrumentation,  methods*
Reg. No./Substance:
34346-01-5/Polyglactin 910

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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