Document Detail

One-hundred aortic valve replacements in octogenarians: outcomes and risk factors for early mortality.
MedLine Citation:
PMID:  17484461     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND AIM OF THE STUDY: Today, ageing of the western population is causing aortic valve surgery to be performed in elderly patients with increasing frequency. The study aim was to evaluate surgical outcome in octogenarian patients undergoing aortic valve replacement (AVR). METHODS: A total of 100 patients (mean age 82.1 +/- 2.7 years; range: 80-95 years) who underwent AVR over a three-year period was reviewed. Concomitant coronary artery bypass grafting was performed in 34% of cases, and a bioprosthesis was implanted in 80%. The mean logistic EuroSCORE was 13.3%. RESULTS: Operative mortality was 8.0%. In multivariate analysis, a logistic EuroSCORE > or =13.5% (p = 0.02), cross-clamp time > or =75 min (p = 0.02) and postoperative acute renal failure were predictors for in-hospital mortality. Follow up was 100% complete; the mean follow up period was 10.6 months. At one year after surgery, the actuarial survival rate of those patients who survived surgery was 86.1%. Postoperative dyspnea at one month (p = 0.004) was the only predictor of short-term mortality. CONCLUSION: Age in itself should not contraindicate surgery, and healthcare systems should be prepared to accommodate elderly patients who may require special resources.
Stefano Urso; Rafael Sadaba; Ernesto Greco; Ivana Pulitani; Luis Alvarez; Arantxa Juaristi; Juan J Goiti
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of heart valve disease     Volume:  16     ISSN:  0966-8519     ISO Abbreviation:  J. Heart Valve Dis.     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-05-08     Completed Date:  2007-07-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9312096     Medline TA:  J Heart Valve Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  139-44     Citation Subset:  IM    
Policlinica Gipuzkoa, Cirugía Cardiaca, San Sebastian, Spain.
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MeSH Terms
Aged, 80 and over
Analysis of Variance
Aortic Valve Insufficiency / epidemiology,  mortality*,  surgery*
Aortic Valve Stenosis / epidemiology,  mortality*,  surgery*
Bioprosthesis / adverse effects
Follow-Up Studies
Heart Valve Prosthesis / adverse effects
Heart Valve Prosthesis Implantation* / instrumentation
Hospital Mortality
Logistic Models
Predictive Value of Tests
Prosthesis Design
Research Design
Risk Factors
Spain / epidemiology
Survival Analysis
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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