Document Detail


One-and-a-half syndrome--two cases.
MedLine Citation:
PMID:  18198796     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
One-and-a-half syndrome is characterized by combination of the clinical features of unilateral horizontal gaze palsy and internuclear ophthalmoplegia. The common symptoms are double vision and oscillopsia. The lesion is located in the paramedian pontine reticular formation, involving the centre of horizontal gaze and medial longitudinal fasciculus. More extensive brainstem damage may result in additional neurological signs. The most frequent underlying diseases are vascular insults, multiple sclerosis, and brainstem tumor. We present two cases of one-and-a-half syndrome. Both patients had lacunar infarction in the paramedian pontine tegmentum, revealed by MRI. The first patient had isolated eye movement disorder, while the second had additional nuclear-type facial paresis. In the first case brainstem evoked potentials indicated brainstem damage, in the second patient it was normal. Ocular symptoms improved within some days in both patients.
Authors:
Sándor Ilniczky; Anita Kamondi; György Várallyay; Barbara Gaal; Agnes Palásti; Szilvia Gulyás; Imre Szirmai
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Ideggyógyászati szemle     Volume:  60     ISSN:  0019-1442     ISO Abbreviation:  Ideggyogy Sz     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2008-01-17     Completed Date:  2008-02-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  17510500R     Medline TA:  Ideggyogy Sz     Country:  Hungary    
Other Details:
Languages:  eng     Pagination:  489-93     Citation Subset:  IM    
Affiliation:
Semmelweis University, Department of Neurology, Budapest. sandor@neur.sote.hu
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MeSH Terms
Descriptor/Qualifier:
Aged
Cerebral Infarction / complications*,  diagnosis*,  pathology,  physiopathology
Diffusion Magnetic Resonance Imaging*
Diplopia / etiology
Evoked Potentials, Visual
Facial Paralysis / etiology
Humans
Male
Ocular Motility Disorders / etiology*
Ophthalmoplegia / etiology
Pons / pathology*
Reticular Formation / pathology*
Syndrome
Tegmentum Mesencephali / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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