Document Detail


Oncolytic virotherapy.
MedLine Citation:
PMID:  23885911     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Oncolytic virotherapy is an emerging technology that uses engineered viruses to treat malignancies. Viruses can be designed with biological specificity to infect cancerous cells preferentially, and to replicate in these cells exclusively. Malignant cells may be killed directly by overwhelming viral infection and lysis, which releases additional viral particles to infect neighboring cells and distant metastases. Viral infections may also activate the immune system, unmask stealthy tumor antigens, and aid the immune system to recognize and attack neoplasms. Delivery of live virus particles is potentially complex, and may require the expertise of the interventional community.
Authors:
Daniel Y Sze; Tony R Reid; Steven C Rose
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of vascular and interventional radiology : JVIR     Volume:  24     ISSN:  1535-7732     ISO Abbreviation:  J Vasc Interv Radiol     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-07-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9203369     Medline TA:  J Vasc Interv Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1115-22     Citation Subset:  IM    
Copyright Information:
Copyright © 2013. Published by Elsevier Inc.
Affiliation:
Division of Interventional Radiology, Stanford Cancer Center, Stanford University School of Medicine, Stanford.
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