Document Detail


Oncologic photodynamic therapy photosensitizers: a clinical review.
MedLine Citation:
PMID:  20510301     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A myriad of naturally occurring and synthetic structures are capable of transferring the energy of light. Few, however, allow for this energy transfer to enable a type II photochemical reaction which, as currently practiced, is a fundamental component of photodynamic therapy. Even fewer of these agents, aptly termed photosensitizers, have found success in the treatment of patients. This review will focus on the oncologic photosensitizers that have come to clinical trial with outcomes published in peer reviewed journals. Based on a clinical orientation the qualities of successful photosensitizers will be examined, how current drugs fare and potential future options explored.
Authors:
Ron R Allison; Claudio H Sibata
Publication Detail:
Type:  Journal Article; Review     Date:  2010-04-21
Journal Detail:
Title:  Photodiagnosis and photodynamic therapy     Volume:  7     ISSN:  1873-1597     ISO Abbreviation:  Photodiagnosis Photodyn Ther     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-31     Completed Date:  2010-10-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101226123     Medline TA:  Photodiagnosis Photodyn Ther     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  61-75     Citation Subset:  IM    
Copyright Information:
(c) 2010 Elsevier B.V. All rights reserved.
Affiliation:
21st Century Oncology, Greenville, NC 27834-3764, USA.
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MeSH Terms
Descriptor/Qualifier:
Antineoplastic Agents / therapeutic use*
Clinical Trials as Topic
Dihematoporphyrin Ether / therapeutic use
Humans
Neoplasms / therapy*
Photochemotherapy*
Photosensitizing Agents*
Chemical
Reg. No./Substance:
0/Antineoplastic Agents; 0/Photosensitizing Agents; 97067-70-4/Dihematoporphyrin Ether

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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