| Omphalocele and gastroschisis in the State of New York, 1992-1999. | |
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MedLine Citation:
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PMID: 14703785 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Variations in the temporal distribution and risk factors for omphalocele and gastroschisis have been suggested although results have not been conclusive. This study examines the trend and risk factors for both conditions among live births in New York State. METHODS: Analysis of surveillance data from the New York Congenital Malformation Registry for the years 1992-1999. RESULTS: Five hundred and ninety-five (595) infants with either omphalocele (287) or gastroschisis (308) were identified. It appeared that the prevalence of gastroschisis was rising from 1992-1999, while prevalence of omphalocele was decreasing. Cases of gastroschisis were clustered among younger mothers while the maternal age distribution among omphalocele infants was U-shaped. As compared to Whites, Black infants were more likely to present with omphalocele (OR = 1.73; 95% confidence interval = 1.28-2.33) and Hispanic infants with gastroschisis (OR = 1.50; 95% CI = 1.12-2.00). For both anomalies, residents of rural New York were significantly at higher risk than those living in urban New York. Twenty-three chromosomal aberrations were detected, all among omphalocele babies. Infant survival was substantially greater among gastroschisis (92%) as compared to omphalocele newborn (81%)[p < 0.0001]. CONCLUSIONS: Prevalence of gastroschisis has been on the rise while that of omphalocele has been declining in New York State. Geographical and racial/ethnic variations were observed, further confirming the notion of different etiologies for the two congenital anomalies. |
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Authors:
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Hamisu M Salihu; Bosny J Pierre-Louis; Charlotte M Druschel; Russell S Kirby |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Birth defects research. Part A, Clinical and molecular teratology Volume: 67 ISSN: 1542-0752 ISO Abbreviation: Birth Defects Res. Part A Clin. Mol. Teratol. Publication Date: 2003 Sep |
Date Detail:
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Created Date: 2004-01-05 Completed Date: 2004-05-19 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 101155107 Medline TA: Birth Defects Res A Clin Mol Teratol Country: United States |
Other Details:
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Languages: eng Pagination: 630-6 Citation Subset: IM |
Affiliation:
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Department of Maternal and Child Health, University of Alabama at Birmingham, Alabama 35294, USA. hsalihu@uab.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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African Continental Ancestry Group Chromosome Aberrations Confidence Intervals European Continental Ancestry Group Female Gastroschisis / diagnosis, epidemiology*, ethnology Hernia, Umbilical / diagnosis, epidemiology*, ethnology Hispanic Americans Humans Infant, Newborn Karyotyping Male Maternal Age Medical Record Linkage New York / epidemiology Odds Ratio Pregnancy Pregnancy Outcome Prevalence Retrospective Studies Rural Population Sex Ratio |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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