Document Detail


Omeprazole-induced cough in a patient with gastroesophageal reflux disease.
MedLine Citation:
PMID:  19801940     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Persistent cough could be caused by various diseases such as postnasal drip syndrome, asthma and gastroesophageal reflux disease (GERD) or adverse event of drugs such as angiotensin-converting enzyme inhibitors. We report a case of persistent cough associated with high plasma levels of the proton pump inhibitor omeprazole in a patient with GERD. This case suggests cough as an adverse drug event to omeprazole, which is otherwise commonly prescribed for the management of GERD-related cough. Therefore, physicians should be aware of the onset or an exacerbation of cough during omeprazole therapy.
Authors:
Ines Reiche; Uwe Tröger; Jens Martens-Lobenhoffer; Arne Kandulski; Helmut Neumann; Peter Malfertheiner; Stefanie M Bode-Böger
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of gastroenterology & hepatology     Volume:  22     ISSN:  1473-5687     ISO Abbreviation:  Eur J Gastroenterol Hepatol     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-10     Completed Date:  2010-09-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9000874     Medline TA:  Eur J Gastroenterol Hepatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  880-2     Citation Subset:  IM    
Affiliation:
Institute of Clinical Pharmacology, Otto-von-Guericke University, Magdeburg, Germany. ines.reiche@med.ovgu.de
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MeSH Terms
Descriptor/Qualifier:
Aged
Cough / chemically induced*,  diagnosis,  etiology
Female
Gastroesophageal Reflux / complications,  drug therapy*
Humans
Omeprazole / adverse effects*,  blood,  therapeutic use
Proton Pump Inhibitors / adverse effects*,  blood,  therapeutic use
Chemical
Reg. No./Substance:
0/Proton Pump Inhibitors; 73590-58-6/Omeprazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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