| Omega-3 polyunsatured fatty acids role in postmyocardial infarction therapy. | |
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MedLine Citation:
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PMID: 12855934 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Largely initiated by studies among Eskimos in the early 1970s, great attention has been given to possible effects of omega-3 polyunsatured fatty acids (PUFA) in cardiovascular diseases. A series of positive effects on pathogenetic mechanisms of cardiovascular disease has been discovered from laboratory studies in cell cultures, animal models and in humans. omega-3 PUFA can reduce platelets and leucocytes activities as well as plasma triglycerides. Moreover they can have antiarrhythmic properties. Nowadays patients who experienced myocardial infarction have decreased risk of total and cardiovascular mortality by treatment with omega-3 PUFA (1 g daily). This effect is present irrespective of high or low fish intake or simultaneous intake of other drugs for secondary prevention of coronary heart disease. Mainly on the basis of GISSI Prevention trial results, dietary supplementation with omega-3 PUFA is now recommended as a new component of secondary prevention after myocardial infarction in national and international guidelines. |
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Authors:
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M Imazio; D Forno; C Quaglia; R Trinchero |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Panminerva medica Volume: 45 ISSN: 0031-0808 ISO Abbreviation: Panminerva Med Publication Date: 2003 Jun |
Date Detail:
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Created Date: 2003-07-11 Completed Date: 2003-10-08 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0421110 Medline TA: Panminerva Med Country: Italy |
Other Details:
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Languages: eng Pagination: 99-107 Citation Subset: IM |
Affiliation:
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Cardiology Department, Maria Vittoria Hospital, Turin, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anti-Arrhythmia Agents / adverse effects, metabolism, therapeutic use* Fatty Acids, Omega-3 / adverse effects, metabolism, therapeutic use* Humans Myocardial Infarction / drug therapy*, prevention & control |
| Chemical | |
Reg. No./Substance:
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0/Anti-Arrhythmia Agents; 0/Fatty Acids, Omega-3 |
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