Document Detail


Omega-3 fatty acids in ileal effluent after consuming different foods containing microencapsulated fish oil powder - an ileostomy study.
MedLine Citation:
PMID:  22992723     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The intestinal absorption of omega-3 long chain polyunsaturated fatty acids (ω(3) LCPUFA), [eicosapentaenoic acid (EPA) + docosahexaenoic acid (DHA)], after consuming fish oil gelatine capsules or different food products fortified with microencapsulated fish oil, was determined using human ileostomates. The total amount of ω(3) LCPUFA consumed per dose of fish oil capsule was 266 mg while that for fortified orange juice, yoghurt and cereal bar was 284 mg per serving of food product. In a time course experiment ω(3) LCPUFA was measured in ileal effluent over 24 h post ingestion. Only 0.58-0.73% of the total ω(3) LCPUFA dose was recovered in the ileal effluent irrespective of whether the fish oil was delivered in a gelatine capsule or in the form of a microencapsulated powder incorporated into fortified foods. Excretion of ω(3) LCPUFA was detected in the 2-18 h effluent collections with none detected at 0 h or 24 h. post ingestion. The transit time of the minimal amount of ω(3) LCPUFA that remained in the ileal effluent was dependent on the method of delivery of the fish oil. The ω(3) LCPUFA content in the ileal effluent peaked at 2-8 h and declined after 10 h after consumption of fish oil capsules and fortified orange juice. In contrast, two peaks in ω(3) LCPUFA content were observed in the ileal effluent, first at 2-8 h and again at 14-16 h, after consumption of fortified yoghurt and cereal bar. The highest recovery of the small amount of ω(3) LCPUFA in the ileal effluent at 14-16 h was obtained when fortified cereal bar was consumed. The results suggest that the delivery of fish oil through food products fortified with microencapsulated fish oil does not compromise the bioavailability of the ω(3) LCPUFA as evidence by no statistical differences detected in the remaining portion of ω(3) LCPUFA in the ileal effluent (p = 0.58). However, the food matrix in which the microencapsulated oil was delivered may alter the transit kinetics of the ω(3) LCPUFA through the small intestine.
Authors:
Luz Sanguansri; Zhiping Shen; Rangika Weerakkody; Mary Barnes; Trevor Lockett; Mary Ann Augustin
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-20
Journal Detail:
Title:  Food & function     Volume:  -     ISSN:  2042-650X     ISO Abbreviation:  Food Funct     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101549033     Medline TA:  Food Funct     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
CSIRO Preventative Health National Research Flagship, Australia. luz.sanguansri@csiro.au.
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