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Omega-3 fatty acids and cardiovascular disease: The epidemiological evidence.
MedLine Citation:
PMID:  21432336     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Epidemiological studies in the last 40 years suggest that omega-3 fatty acids derived from fish and fish oil decrease the risk of coronary heart disease, hypertension and stroke, and their complications. The beneficial effects of omega-3 fatty acids include effects on lipids, blood pressure, cardiac and vascular function, eicosanoids, coagulation, and immunological responses. However, not all population studies have shown that omega-3 fatty acids are associated with reduced rates of coronary mortality. Such studies suffer either from small numbers of subjects or the population already had a high intake of fish. When comparing the highest intake of fish to that of the lowest fish intake, the beneficial effects of omega-3 fatty acids have been shown. In population-based case-control studies, the patients consuming modest amounts of fish, the equivalent of one fatty fish meal per week, had a significant lower risk of primary cardiac arrest compared with those who did not eat fish at all. In case-control studies, the intake of eicosapentaenoic acid and docosahexaenoic acid as reflected in adipose tissue content is inversely associated with risk of myocardial infarction.
Artemis P Simopoulos
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Environmental health and preventive medicine     Volume:  6     ISSN:  1342-078X     ISO Abbreviation:  Environ Health Prev Med     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2011-03-24     Completed Date:  2012-10-02     Revised Date:  2013-05-23    
Medline Journal Info:
Nlm Unique ID:  9609642     Medline TA:  Environ Health Prev Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  203-9     Citation Subset:  -    
The Center for Genetics, Nutrition and Health, 2001 S. Street. N. W., Suite 530, 20009, Washington, D.C., U.S.A.,
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