| Omaha childhood blood lead and environmental lead: a linear total exposure model. | |
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MedLine Citation:
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PMID: 6489285 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The majority of experimental and population studies of blood lead (PbB) and environmental lead, including the Omaha study, have utilized the Goldsmith-Hexter log-log or power function model. Comparison was made of the log-log model and a linear model of total exposure to describe the Omaha Study of 1074 PbBs from children ages 1-18 years as related to air (PbA), soil (PbS), and housedust (PbHD) lead. The data fit of the linear model was statistically equivalent to the power model and the predicted curves were biologically more plausible. The linear model avoids the mathematical limitations of the power model which predicts PbB zero at PbA zero. From the Omaha data, this model, ln PbB = ln (beta 0 + B1 PbA + B2 PbS + beta 3 PbHD) predicts that PbB increases 1.92 micrograms/dl as PbA increases 1.0 microgram/m3. Since PbS and PbHD increase with PbA, however, the increases in total exposure predict a PbB increase of 4-5 micrograms/dl as PbA increases 1.0 microgram/m3. |
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Authors:
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C R Angle; A Marcus; I H Cheng; M S McIntire |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Environmental research Volume: 35 ISSN: 0013-9351 ISO Abbreviation: Environ. Res. Publication Date: 1984 Oct |
Date Detail:
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Created Date: 1984-12-03 Completed Date: 1984-12-03 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0147621 Medline TA: Environ Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 160-70 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Air Pollutants / analysis Child Child, Preschool Dust / analysis Environmental Pollutants / analysis* Humans Infant Lead / analysis, blood* Nebraska Soil Pollutants / analysis Statistics as Topic Suburban Population Urban Population |
| Grant Support | |
ID/Acronym/Agency:
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1 R01 ES 01857/ES/NIEHS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Air Pollutants; 0/Dust; 0/Environmental Pollutants; 0/Soil Pollutants; 7439-92-1/Lead |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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