Document Detail


Omaha childhood blood lead and environmental lead: a linear total exposure model.
MedLine Citation:
PMID:  6489285     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The majority of experimental and population studies of blood lead (PbB) and environmental lead, including the Omaha study, have utilized the Goldsmith-Hexter log-log or power function model. Comparison was made of the log-log model and a linear model of total exposure to describe the Omaha Study of 1074 PbBs from children ages 1-18 years as related to air (PbA), soil (PbS), and housedust (PbHD) lead. The data fit of the linear model was statistically equivalent to the power model and the predicted curves were biologically more plausible. The linear model avoids the mathematical limitations of the power model which predicts PbB zero at PbA zero. From the Omaha data, this model, ln PbB = ln (beta 0 + B1 PbA + B2 PbS + beta 3 PbHD) predicts that PbB increases 1.92 micrograms/dl as PbA increases 1.0 microgram/m3. Since PbS and PbHD increase with PbA, however, the increases in total exposure predict a PbB increase of 4-5 micrograms/dl as PbA increases 1.0 microgram/m3.
Authors:
C R Angle; A Marcus; I H Cheng; M S McIntire
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Environmental research     Volume:  35     ISSN:  0013-9351     ISO Abbreviation:  Environ. Res.     Publication Date:  1984 Oct 
Date Detail:
Created Date:  1984-12-03     Completed Date:  1984-12-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0147621     Medline TA:  Environ Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  160-70     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Air Pollutants / analysis
Child
Child, Preschool
Dust / analysis
Environmental Pollutants / analysis*
Humans
Infant
Lead / analysis,  blood*
Nebraska
Soil Pollutants / analysis
Statistics as Topic
Suburban Population
Urban Population
Grant Support
ID/Acronym/Agency:
1 R01 ES 01857/ES/NIEHS NIH HHS
Chemical
Reg. No./Substance:
0/Air Pollutants; 0/Dust; 0/Environmental Pollutants; 0/Soil Pollutants; 7439-92-1/Lead

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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