Document Detail

Oligonucleotide-stabilized fluorescent silver nanoclusters for turn-on detection of melamine.
MedLine Citation:
PMID:  22575638     Owner:  NLM     Status:  Publisher    
Fluorescence nanoclusters have been used for the determination of melamine for the first time. The method is based on the fluorescence turn-on of oligonucleotide-stabilized silver nanoclusters (DNA-Ag NCs) by melamine. The enhancement factors (I-I(0))/I(0) increase linearly with melamine concentrations over the range 5.0×10(-8)-7.0×10(-6)M (R(2)=0.998). The detection limit is 1.0×10(-8)M, which is approximately 2000 times lower than the US Food and Drug Administration estimated melamine safety limit of 20.0μM. Furthermore, the milk samples spiked with melamine are analyzed with excellent recoveries.
Shuang Han; Shuyun Zhu; Zhongyuan Liu; Lianzhe Hu; Saima Parveen; Guobao Xu
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-26
Journal Detail:
Title:  Biosensors & bioelectronics     Volume:  -     ISSN:  1873-4235     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-5-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9001289     Medline TA:  Biosens Bioelectron     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier B.V. All rights reserved.
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China; Graduate University of the Chinese Academy of Sciences, Beijing 100039, China.
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