Document Detail

Oligonephropathy, developmental programming and nutritional management of low-gestation newborns.
MedLine Citation:
PMID:  16497634     Owner:  NLM     Status:  MEDLINE    
Intrauterine growth retardation is associated with oligonephropathy and the risk of hypertension and renal disease in adulthood. Animal study data show that nephron density is directly related to protein nutrition status during nephrogenesis. Among infants born at low gestation, postnatal growth retardation and major deficits in energy and protein intake have been reported. Conclusion: Since nephrogenesis occurs mainly in late gestation, increasing protein intake during nephrogenesis could minimize the risk of long-term morbidities associated with oligonephropathy.
Melinda Y Yeung
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  95     ISSN:  0803-5253     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-02-24     Completed Date:  2006-06-28     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  263-7     Citation Subset:  IM    
Department of Pharmacy, The Children's Hospital at Westmead, New South Wales, Australia.
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MeSH Terms
Cardiovascular Diseases / prevention & control*
Fetal Growth Retardation / pathology*
Infant Nutritional Physiological Phenomena*
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / prevention & control*
Kidney Diseases / prevention & control*
Nephrons / embryology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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