Document Detail


Olfactory function in primary open-angle glaucoma patients.
MedLine Citation:
PMID:  20408073     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The aim of this study was to assess the olfactory function of primary open-angle glaucoma patients. PATIENTS AND METHODS: We analyzed odour threshold, identification, and discrimination in 30 primary open-angle glaucoma patients and 30 age- and gender-matched healthy control subjects. The "Sniffin' Sticks" test battery was applied sequentially on both sides, scores of two nostrils were averaged and means were compared with Mann-Whitney U-test between the groups. RESULTS: Scores for odour threshold were 5.9 +/- 2.2 and 7.4 +/- 2.1 in glaucoma and control group, respectively (p = 0.01), for odour discrimination 10.5 +/- 2.0 and 10.8 +/- 1.6 (p = 0.65), and for odour identification 11.8 +/- 2.1 and 10.6 +/- 1.6 (p = 0.008). Comparing within glaucoma group between those with (n = 18) and without history (n = 12) of cold hands and feet, the former had significantly better odour threshold scores, 6.6 +/- 1.5, than the latter, 4.8 +/- 2.6 (p = 0.036); no difference in other two olfactory modalities were detected. CONCLUSION: Changes of olfactory function have been described in neurodegenerations such as Alzheimer and Parkinson diseases. Complex alterations of olfactory performance seem to be present in POAG patients as well.
Authors:
K Gugleta; A Kochkorov; R Katamay; A Husner; A Welge-L?ssen; J Flammer; S Org?l
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-04-20
Journal Detail:
Title:  Klinische Monatsbl?tter f?r Augenheilkunde     Volume:  227     ISSN:  1439-3999     ISO Abbreviation:  Klin Monbl Augenheilkd     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-21     Completed Date:  2010-05-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0014133     Medline TA:  Klin Monbl Augenheilkd     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  277-9     Citation Subset:  IM    
Copyright Information:
Copyright Georg Thieme Verlag KG Stuttgart . New York.
Affiliation:
Ophthalmology Department, University Hospital Basel, Basel, Switzerland. gugletak@uhbs.ch
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MeSH Terms
Descriptor/Qualifier:
Aged
Female
Glaucoma, Open-Angle / complications*,  diagnosis,  physiopathology*
Humans
Male
Middle Aged
Olfaction Disorders / diagnosis,  etiology*,  physiopathology*
Sensory Thresholds
Smell*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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