Document Detail

Olfactory function in patients with and without temporal lobe resection.
MedLine Citation:
PMID:  23153710     Owner:  NLM     Status:  Publisher    
OBJECTIVES: The study aimed to assess olfactory function in patients with temporal lobe epilepsy before and after resection of temporal lobe structures and especially addressed the question whether there are any significant olfactory differences as a function of side of epileptic focus or resection. MATERIALS AND METHODS: Thirteen pre- and 22 postoperative patients and 35 age- and sex-matched healthy controls underwent olfactory testing by means of the Sniffin' Sticks testing device (comprehensive measurement of threshold, discrimination, and identification abilities). RESULTS: Patients with unilateral epileptic focus but without temporal lobe resection tended to have impaired identification abilities only compared to the healthy controls. There were no significant differences in olfactory function on the side of the epileptic focus compared to the non-affected side. However, the patients after temporal lobe resection presented with significantly impaired bilateral discrimination and identification abilities compared to the healthy controls and with lower olfactory scores on the side of the lesion compared to the non-lesioned side. CONCLUSIONS: Olfactory function is only partially impaired preoperatively and will deteriorate further after the partial resection on the side of the lesion.
Antje Haehner; Sophia Henkel; Peter Hopp; Susanne Hallmeyer-Elgner; Ulrike Reuner; Heinz Reichmann; Thomas Hummel
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-12
Journal Detail:
Title:  Epilepsy & behavior : E&B     Volume:  25     ISSN:  1525-5069     ISO Abbreviation:  Epilepsy Behav     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100892858     Medline TA:  Epilepsy Behav     Country:  -    
Other Details:
Languages:  ENG     Pagination:  477-480     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Smell & Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School, Dresden, Germany. Electronic address:
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