Document Detail

Olfactory function in patients with chronic rhinosinusitis before and after functional endoscopic sinus surgery.
MedLine Citation:
PMID:  18702914     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The olfactory loss in patients with chronic rhinosinusitis has been measured by different methods. However, the results have been variable and it is not clear whether functional endoscopic sinus surgery (FESS) significantly improves olfactory function. This study was performed to evaluate the influences of FESS on olfactory function in patients with chronic rhinosinusitis using three different types of olfactory tests. METHODS: Seventy patients with chronic rhinosinusitis were administered the University of Pennsylvania Smell Identification Test (UPSIT), a single staircase phenyl ethyl alcohol odor detection threshold test (STT), and a short-term odor memory/discrimination test a day before and 6 months after FESS. A questionnaire inquiring about the patients' self-perception of olfactory function was administered also. Independent ratings of the severity of chronic rhinosinusitis before FESS were established from CT scans. RESULTS: Fifty-two (74.3%) of the patients reported that their olfactory function was impaired before surgery, and 68.6% of the patients reported impaired olfactory function after surgery, a difference that was not significant. No meaningful changes in any of the olfactory test scores were noted 6 or more months after FESS. Preoperatively, small correlations between CT scores and the symptom scores (r = 0.278; p = 0.024), threshold scores (r = -0.27; p = 0.031), and UPSIT scores (r = -0.36; p = 0.003) were observed. CONCLUSION: In patients with severe rhinosinusitis, FESS had little impact on the ability to smell, regardless of the method for assessing smell function. Subtle associations between olfactory function and the severity of chronic rhinosinusitis determined by CT were observed, however, preoperatively. The olfactory test measures were correlated with one another both pre- and postoperatively.
Rong-San Jiang; Fung-Jou Lu; Kai-Li Liang; Jiun-Yi Shiao; Mao-Chang Su; Chung-Han Hsin; Wen-Kang Chen
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of rhinology     Volume:  22     ISSN:  1050-6586     ISO Abbreviation:  Am J Rhinol     Publication Date:    2008 Jul-Aug
Date Detail:
Created Date:  2008-08-15     Completed Date:  2008-10-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807268     Medline TA:  Am J Rhinol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  445-8     Citation Subset:  IM    
Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan.
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MeSH Terms
Aged, 80 and over
Chronic Disease
Follow-Up Studies
Middle Aged
Otorhinolaryngologic Surgical Procedures / methods*
Rhinitis / complications,  physiopathology*,  surgery
Severity of Illness Index
Sinusitis / complications,  physiopathology*,  surgery
Smell / physiology*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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