Document Detail

Olfactory deficits in patients with anorexia nervosa.
MedLine Citation:
PMID:  20821739     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Patients with anorexia nervosa (AN) often show gastrointestinal symptoms and have altered gastrointestinal functions. Olfaction is part of the predigestive function and plays an important role in the selection of food and the control of food intake. The question arises if patients with eating disorders have changes in olfactory functions as well. The aim of this study was to compare olfactory functions in patients with AN and controls using the Sniffin' sticks.
METHOD: We studied 19 patients with AN, restricting type (10 patients) and binge-eating/purging type (9 patients) and 21 healthy controls matched by age. For evaluation of the severity of AN we used the Eating Disorder Inventory-2 (EDI-2).
RESULTS: Differences were found in odour identification with patients with AN having lower scores and there was a significant correlation between results in this subtest and BMI. There were no differences in odour threshold, odour discrimination and overall performance. There was no correlation between test results and EDI-2 scores. We did not find differences between subtypes of AN.
CONCLUSIONS: Larger and more homogenous samples are needed to gain a better understanding of degree and type of olfactory deficits in AN-patients with possible consequences for refeeding therapy.
Nora Rapps; Katrin Elisabeth Giel; Emely Söhngen; Anna Salini; Paul Enck; Stephan C Bischoff; Stephan Zipfel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European eating disorders review : the journal of the Eating Disorders Association     Volume:  18     ISSN:  1099-0968     ISO Abbreviation:  Eur Eat Disord Rev     Publication Date:    2010 Sep-Oct
Date Detail:
Created Date:  2010-09-07     Completed Date:  2010-12-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9436977     Medline TA:  Eur Eat Disord Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  385-9     Citation Subset:  IM    
Department of Psychosomatic Medicine and Psychotherapy, Medical University Hospital Tuebingen, Tuebingen, Germany.
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MeSH Terms
Anorexia Nervosa / physiopathology*,  psychology
Body Mass Index
Bulimia / physiopathology*,  psychology
Case-Control Studies
Discrimination (Psychology) / physiology
Olfaction Disorders / physiopathology*,  psychology
Olfactory Perception / physiology*
Psychiatric Status Rating Scales / statistics & numerical data
Sensory Thresholds / physiology
Smell / physiology*

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