| Olfactory bulbectomy counteracts inhibitory effect of food restriction on reproductive function. | |
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MedLine Citation:
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PMID: 8024044 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Previous studies have shown that bilateral removal of the olfactory bulbs (BX) results in a large increase in gonadotropin secretion in golden hamsters. The principal question addressed by the present study was whether BX would offset the inhibitory effect of food restriction on reproductive function. BX or sham (SH) BX male golden hamsters were fed ad libitum or were restricted to only enough food to maintain them at 70% of the body weight of control groups fed ad libitum. The SH-70% group underwent marked testicular regression after approximately 6-8 wk, but the testes size of the BX-70% hamsters decreased only in proportion to the decrease in body weight. The BX food-restricted group had to be fed more food to maintain the same weight as the SH-70% hamsters, and the BX-70% group also had a higher core body temperature, lower percent body fat, and higher serum free thyroxine levels than SH food-restricted animals. In summary, removal of the olfactory bulbs appears to facilitate tonic gonadotropin secretion, such that food restriction is no longer capable of inducing testicular regression. In addition, the olfactory bulbs may have a strong influence on metabolic function in golden hamsters. |
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Authors:
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D R Pieper; C A Lobocki; K H Karo |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of physiology Volume: 266 ISSN: 0002-9513 ISO Abbreviation: Am. J. Physiol. Publication Date: 1994 Jun |
Date Detail:
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Created Date: 1994-08-02 Completed Date: 1994-08-02 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370511 Medline TA: Am J Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: R1891-5 Citation Subset: IM |
Affiliation:
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Department of Physiology, Providence Hospital, Southfield, Michigan 48037. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adipose Tissue
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anatomy & histology Animals Body Temperature Body Weight Cricetinae Eating Food Deprivation / physiology* Gonadal Steroid Hormones / blood Male Motor Activity / physiology Olfactory Bulb / physiology* Organ Size Reproduction* Testis / anatomy & histology |
| Chemical | |
Reg. No./Substance:
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0/Gonadal Steroid Hormones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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