Document Detail

Olfactory bulb volume in smokers.
MedLine Citation:
PMID:  23212471     Owner:  NLM     Status:  MEDLINE    
The study aimed to investigate the volume of the olfactory bulb in smokers. Specifically, we wanted to see whether environmental influences may exert a negative influence on OB structure. Twenty-one smokers and 59 non-smokers, matched for age and sex, underwent olfactory testing by means of the Sniffin' Sticks testing device (measurement of odor threshold and identification abilities). In addition, they underwent an MR scan with 2-mm-thick T2-weighted fast spin-echo images without interslice gap in the coronal plane covering the anterior and middle segments of the base of the skull. Olfactory function was not different between the 2 groups; however, olfactory bulb volumes were smaller in smokers than in non-smokers (p = 0.006). The deficit seen at the level of the OB did not correlate with the duration of smoking. The current data indicate that smoking may have a negative effect on the olfactory system before this becomes obvious in terms of a decreased olfactory function.
Valentin A Schriever; Nicole Reither; Johannes Gerber; Emilia Iannilli; Thomas Hummel
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-12-02
Journal Detail:
Title:  Experimental brain research     Volume:  225     ISSN:  1432-1106     ISO Abbreviation:  Exp Brain Res     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-20     Completed Date:  2013-08-05     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  0043312     Medline TA:  Exp Brain Res     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  153-7     Citation Subset:  IM    
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MeSH Terms
Magnetic Resonance Imaging
Olfactory Bulb / pathology*,  physiopathology
Olfactory Perception / physiology*
Organ Size
Sensory Thresholds / physiology
Smell / physiology*
Smoking / pathology*,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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