Document Detail

Olfactory bulb volume in Taiwanese patients with posttraumatic anosmia.
MedLine Citation:
PMID:  19958606     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Olfactory bulb (OB) volume has been shown to be an indicator of olfactory function. However, few studies have been done in Asia to investigate the influence of different disorders on OB volume.
METHODS: Data from patients with posttraumatic anosmia were collected in our department. Their olfactory thresholds were assessed by the phenyl ethyl alcohol threshold test. They were treated with a course of high-dose steroid, and followed up for at least 3 months without any olfactory improvement. Magnetic resonance imaging was subsequently used to measure patients' OB volumes. Subjects who self-reported their olfactory function was normal were also included in the control group for comparison.
RESULTS: Fifty-four patients with posttraumatic anosmia and 30 subjects who self-reported their olfactory function was normal were enrolled in this study. The mean right OB volume was 45.2 mm3, and the mean left OB volume was 46.3 mm3 in patients with posttraumatic anosmia. The mean right OB volume was 59.7 mm3, and the mean left OB volume was 66.0 mm3 in control subjects. The OB volumes were significantly lower in patients with posttraumatic anosmia.
CONCLUSION: OB volumes were significantly lower in Taiwanese patients with posttraumatic anosmia.
Rong-San Jiang; Jyh-Wen Chai; Wen-Hsien Chen; Wen-Bin Fuh; Chin-Ming Chiang; Clayton Chi-Chang Chen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of rhinology & allergy     Volume:  23     ISSN:  1945-8932     ISO Abbreviation:  Am J Rhinol Allergy     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2009-12-04     Completed Date:  2010-06-09     Revised Date:  2011-11-10    
Medline Journal Info:
Nlm Unique ID:  101490775     Medline TA:  Am J Rhinol Allergy     Country:  United States    
Other Details:
Languages:  eng     Pagination:  582-4     Citation Subset:  IM    
Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan.
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MeSH Terms
Craniocerebral Trauma / complications*
Follow-Up Studies
Middle Aged
Olfaction Disorders / diagnosis,  drug therapy,  etiology*,  pathology*
Olfactory Bulb / pathology*
Olfactory Perception*
Organ Size
Sensory Thresholds
Steroids / therapeutic use
Reg. No./Substance:

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