| Olfactory bulb volume in Taiwanese patients with posttraumatic anosmia. | |
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MedLine Citation:
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PMID: 19958606 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Olfactory bulb (OB) volume has been shown to be an indicator of olfactory function. However, few studies have been done in Asia to investigate the influence of different disorders on OB volume. METHODS: Data from patients with posttraumatic anosmia were collected in our department. Their olfactory thresholds were assessed by the phenyl ethyl alcohol threshold test. They were treated with a course of high-dose steroid, and followed up for at least 3 months without any olfactory improvement. Magnetic resonance imaging was subsequently used to measure patients' OB volumes. Subjects who self-reported their olfactory function was normal were also included in the control group for comparison. RESULTS: Fifty-four patients with posttraumatic anosmia and 30 subjects who self-reported their olfactory function was normal were enrolled in this study. The mean right OB volume was 45.2 mm3, and the mean left OB volume was 46.3 mm3 in patients with posttraumatic anosmia. The mean right OB volume was 59.7 mm3, and the mean left OB volume was 66.0 mm3 in control subjects. The OB volumes were significantly lower in patients with posttraumatic anosmia. CONCLUSION: OB volumes were significantly lower in Taiwanese patients with posttraumatic anosmia. |
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Authors:
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Rong-San Jiang; Jyh-Wen Chai; Wen-Hsien Chen; Wen-Bin Fuh; Chin-Ming Chiang; Clayton Chi-Chang Chen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of rhinology & allergy Volume: 23 ISSN: 1945-8932 ISO Abbreviation: Am J Rhinol Allergy Publication Date: 2009 Nov-Dec |
Date Detail:
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Created Date: 2009-12-04 Completed Date: 2010-06-09 Revised Date: 2011-11-10 |
Medline Journal Info:
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Nlm Unique ID: 101490775 Medline TA: Am J Rhinol Allergy Country: United States |
Other Details:
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Languages: eng Pagination: 582-4 Citation Subset: IM |
Affiliation:
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Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Craniocerebral Trauma / complications* Female Follow-Up Studies Humans Male Middle Aged Olfaction Disorders / diagnosis, drug therapy, etiology*, pathology* Olfactory Bulb / pathology* Olfactory Perception* Organ Size Sensory Thresholds Steroids / therapeutic use Taiwan |
| Chemical | |
Reg. No./Substance:
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0/Steroids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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