| Olfactory bulb ventricles as a frequent finding--a myth or reality? Evaluation using high resolution 3 Tesla magnetic resonance imaging. | |
| | |
MedLine Citation:
|
PMID: 21044659 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
Data on the prevalence of persistent olfactory bulb ventricles (OBV) in humans remain contradictory. The aim of this study was to investigate the hypothesis of large cystic-like OBVs filled with cerebrospinal fluid (CSF) as a frequent finding in magnetic resonance imaging (MRI). Fifty normosmic volunteers (25 men and 25 women, mean 40 years) underwent 3 Tesla MRI of the anterior skull base. Normal smell function was determined by testing of the odor threshold discrimination identification score using the Sniffin' Sticks test kit. The voxel size of the constructive interference in steady state (CISS) sequence was 0.4×0.4×0.4 mm (TR 12.18 ms, TE 6.09 ms) using a 12-channel head coil. Image quality was rated by three observers according to predefined criteria on an ordinal scale. Additionally, contrast-to-noise (CNR) and signal-to-noise (SNR) ratios were calculated. Quantitative signal intensity (SI) measurement of olfactory bulb (OB) structures and small Virchow-Robin spaces (VRS) was performed using multi planar reconstruction mode. Ninety-one OBs were eligible for evaluation. Image quality was rated as adequate in 55% and as excellent in 36% of cases. CNR and SNR calculations resulted in values of 21.59 and 19.06, respectively. Wilcoxon signed rank test revealed significant higher SI values for OB center compared to OB surface (P<0.001) and to OB base (P<0.001) but also significant lower SI values compared to small VRS (P<0.001) in 94.5%. In 5.5%, SI measurement revealed signs for CSF-filled structures in the OB. High-resolution 3 Tesla MRI did not verify the hypothesis of large cystic CSF-filled OBVs as a frequent finding although evidence is growing that the hyperintense signal in the center of OBs might be associated with interstitial or finely dispersed CSF/fluid or with tiny, histologically detectable remnants of OBVs. |
| | |
Authors:
|
H P Burmeister; T Bitter; P A T Baltzer; M Dietzel; O Guntinas-Lichius; H Gudziol; W A Kaiser |
Related Documents
:
|
19119909 - Active spontaneous decompression of a suprasellar-prepontine arachnoid cyst detected wi... 16815019 - Epidural extension of a lumbar vertebral haemangioma. 21456529 - Synthesis of gadolinium nanoscale metal-organic framework with hydrotropes: manipulatio... 16517969 - Technical review and considerations for a cerebrospinal fluid leakage study. 12059829 - Prediction by computerised tomography of distance from skin to epidural space during th... 7737869 - Headache and cysticercosis in ecuador, south america. 3877439 - Computed tomography in stage iii neuroblastoma. 19066199 - Neuroimaging of the wernicke-korsakoff syndrome. 21978669 - Cardiovascular magnetic resonance activity in the united kingdom - a survey on beha... |
Publication Detail:
|
Type: Journal Article Date: 2010-10-31 |
Journal Detail:
|
Title: Neuroscience Volume: 172 ISSN: 1873-7544 ISO Abbreviation: Neuroscience Publication Date: 2011 Jan |
Date Detail:
|
Created Date: 2010-12-27 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7605074 Medline TA: Neuroscience Country: United States |
Other Details:
|
Languages: eng Pagination: 547-53 Citation Subset: IM |
Copyright Information:
|
Crown Copyright © 2011. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
|
Institute of Diagnostic and Interventional Radiology, Department of Otorhinolaryngology, University Hospital-Friedrich Schiller University Jena, Philosophenweg 3, D-07740 Jena, Germany. hartmut.burmeister@med.uni-jena.de |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Salicylate induced neural changes in the primary auditory cortex of awake cats.
Next Document: Chronic stress alters neural activity in medial prefrontal cortex during retrieval of extinction.